High Concentration Formulations of Recombinant Human Interleukin-1 Receptor Antagonist: I. Physical Characterization
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چکیده
منابع مشابه
Cloning, Expression and Characterization of Recombinant Human Fc Receptor Like 1, 2 and 4 Molecules
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IL-1ra is the first described naturally occurring receptor antagonist of any cytokine or hormone-like molecule. IL-1ra is a member of the IL-1 family by three criteria: amino acid sequence homology of 26 to 30% to IL-1 beta and 19% to IL-1 alpha; similarities in gene structure; and common gene localization to human chromosome 2q14. Two structural variants of IL-1ra exist: sIL-1ra, a secretory m...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2008
ISSN: 0022-3549
DOI: 10.1002/jps.21199